Associate Professor Biomedical Engineering Rensselaer Polytechnic Institute Niskayuna, New York, United States
Introduction: : Abstract: I’ve recently returned to academia from an industrial research site, where I worked on projects focused on understanding and applying the fundamental science behind ultrasound neuromodulation. As I begin a new chapter of my research career in an academic position, I’ll discuss the original development of the ultrasound neuromodulation tools, and original uses in pre-clinical models of chronic inflammatory and metabolic diseases. I’ll point out key/fundamental first experiments that led to new strategic understanding of non-invasive peripheral neuromodulation, highlight scientific insights that were key in developing proof-of-concept clinical trials, and then discuss remaining questions and unknowns that need to be addressed for continued development and translation of this promising new technology.
Materials and
Methods: : Material and Methods to be included in invited talk; discussion will be on ultrasound systems, pre-clinical models, translation clinical studies during industrial clinical translation. Final discussion will be on remaining methods/techniques necessary to further discern the mechanism behind ultrasound neuromodulation in the periphery, and better design translation tools and clinical protocols.
Results, Conclusions, and Discussions:: Results and conclusions to be included in invited talk; results will be on a range of papers/publications from a 5–8-year period building up from initial in vitro and pre-clinical discovery to preparation and testing in pilot clinical trials. Attention will be paid to new techniques available, and improvemetn that can be made in future generation of ultrasound neuromodulation systems.