Computational Modeling and Machine Learning in Drug Delivery

Track Chair(s)

• 

  Elizabeth Barker, PhD

  Assistant Professor
  University of Tennessee
  Knoxville, Tennessee, United States
• 

  Jyothi Menon, PhD

  Associate Professor
  Texas A&M University
  College Station, Texas, United States

Session Chair(s)

• 

  Ninghao Zhu, PhD

  Assistant Professor
  Kansas State University
  Manhattan, Kansas, United States
• 

  Janny Pineiro, PhD

  Research Assistant Professor
  University of Florida, Florida, United States

Presentations:

• 1:15 PM - 1:30 PM PDT

  Machine learning and active targeting enhance mRNA lipid nanoparticle delivery to B cells ex vivo and in vivo
  

  Presenting Author: Leonardo Cheng – The Johns Hopkins University

  Co-Author: Brandon Chang – Johns Hopkins University

  Co-Author: Wu Han Toh – Johns Hopkins University

  Co-Author: Gene Weng – Johns Hopkins University

  Co-Author: Jin Liu – Johns Hopkins University

  Co-Author: Joseph Choy – Johns Hopkins University

  Co-Author: Xiaoya Lu – Johns Hopkins University

  Co-Author: Jinghan Lin – Johns Hopkins University

  Co-Author: Autumn Greco – Johns Hopkins University

  Co-Author: Yining Zhu – Johns Hopkins University

  Co-Author: Ramya Kumar – Colorado School of Mines

  Co-Author: Stephany Tzeng – Johns Hopkins

  Co-Author: Maximilian F. Konig, MD – The Johns Hopkins University School of Medicine

  Co-Author: Jordan Green – Johns Hopkins University

  Last Author: Hai-Quan Mao, PhD – Johns Hopkins University

  Primary Investigator: Hai-Quan Mao, PhD – Johns Hopkins University
• 1:30 PM - 1:45 PM PDT

  FALCON: A Machine Learning-Driven Platform for Multi-Objective Optimization of Lipid Nanoparticle Composition Towards Cell Type-Selective Transfection
  

  Presenting Author: Wu Han Toh – Johns Hopkins University

  Co-Author: Leonardo Cheng – Johns Hopkins University

  Co-Author: Di Yu – Johns Hopkins University

  Co-Author: Brandon Chang – Johns Hopkins University

  Co-Author: Gene Weng – Johns Hopkins University

  Primary Investigator: Hai-Quan Mao, PhD – Johns Hopkins University
• 1:45 PM - 2:00 PM PDT

  Machine Learning-Accelerated Discovery of Stable Solid-State Lipid Nanoparticle-Formulated RNA Vaccines
  

  Presenting Author: Jinbi Tian – MIT (EECS)

  Co-Author: Khanh Tran – MIT-Koch Institute

  Co-Author: Olivia Sheridan – MIT

  Co-Author: Sevinj Mursalova – MIT-Koch Institute

  Co-Author: Daniel Antov – MIT (BE)

  Co-Author: Robert Langer – MIT-Koch Institute

  Co-Author: Mina Luković – MIT (EECS)

  Last Author: Ana Jaklenec, PhD – MIT-Koch Institute

  Primary Investigator: Ana Jaklenec, PhD – MIT-Koch Institute

  Co-Author: Brett Pogostin, PhD – MIT
• 2:00 PM - 2:15 PM PDT

  Computational Modeling of Intravascular and Perivascular Transport of Active Nanoparticles to Target Sites
  

  Presenting Author: Shoaib A. Goraya, PhD – Brigham and Women's Hospital, Harvard Medical School

  Co-Author: Farhad R. Nezami – Harvard Medical School

  Co-Author: Arif Masud, PhD – University of Illinois Urbana Champaign

  Last Author: Arif Masud, PhD – University of Illinois Urbana Champaign

  Primary Investigator: Arif Masud, PhD – University of Illinois Urbana Champaign

  Co-Author: Hyunjoon Kong, PhD – University of Illinois at Urbana-Champaign
• 2:15 PM - 2:30 PM PDT

  Machine Learning and Automation to Optimize Hydrogel Release Profiles
  

  Presenting Author: Cristian Lopez – Rutgers University

  Last Author: Adam Gormley – Rutgers University

  Primary Investigator: Adam Gormley – Rutgers University

  Co-Author: Chee Meng Eugene Cheong – Rutgers University
• 2:30 PM - 2:45 PM PDT

  Refillable Cartridge-based Microfluidic Peristaltic Pump System for Targeted Neurological Drug Delivery
  

  Presenting Author: Haowei Ma – Department of Mechanical and Aerospace Engineering, Case School of Engineering, Case Western Reserve University (CWRU)

  Co-Author: Allison Hess-Dunning – Department of Biomedical Engineering, Case Western Reserve University (CWRU)

  Last Author: Melinda Lake-Speers – Department of Mechanical and Aerospace Engineering, Case School of Engineering, Case Western Reserve University (CWRU)

  Primary Investigator: Melinda Lake-Speers – Department of Mechanical and Aerospace Engineering, Case School of Engineering, Case Western Reserve University (CWRU)