Mechanosensing in Cancer

Track Chair(s)

• 

  Priscilla Hwang, PhD

  Associate Professor
  Virginia Commonwealth University
  Richmond, Virginia, United States
• CR

  Claire Robertson, PhD

  Materials Engineer
  Lawrence Livermore National Laboratory
  Livermore, California, United States

Session Chair(s)

• 

  Adam Engler

  Professor and Department Chair
  University of California San Diego
  La Jolla, California, United States
• 

  Jian Zhang, PhD

  Assistant Professor
  University of Arkansas, United States

Presentations:

• 8:30 AM - 9:00 AM PDT

  Cancer Cell Mechanosensing: How Confinement, Stiffness and Fluid Viscosity Shape Cell Function
  

  Invited Speaker: Konstantinos Konstantopoulos, PhD – Johns Hopkins University
• 9:00 AM - 9:15 AM PDT

  Nuclear envelope protein lamin A can define breast cancer cell phenotype.
  

  Presenting Author: Sarah Henretta – Cornell University

  Primary Investigator: Sarah Henretta – Cornell University

  Co-Author: Karisa Bockley – Cornell University

  Last Author: Jan Lammerding, PhD – Cornell University
• 9:15 AM - 9:30 AM PDT

  Ferroptosis is regulated by matrix mechanics
  

  Presenting Author: Emma Villares – Duke University

  Co-Author: Chao-Chieh Lin – Duke University

  Co-Author: Jen-Tsan Ashley Chi – Duke University

  Primary Investigator: Sharon Gerecht – Duke University
• 9:30 AM - 9:45 AM PDT

  Extracellular matrix stiffness promotes cell division errors, chromosome loss and genetic variation in 3D tumor spheroids
  

  Presenting Author: Alişya Anlaş, PhD – University of Pennsylvania

  Primary Investigator: Dennis Discher – University of Pennsylvania
• 9:45 AM - 10:00 AM PDT

  Prolonged Preconditioning to Elevated Fluid Viscosity Imprints Memory and Promotes Cancer Cell Motility and Metastasis
  

  Presenting Author: Anindya Sen – JOHNS HOPKINS UNIVERSITY

  Co-Author: Debanik Choudhury – Johns Hopkins University

  Co-Author: Kaustav Bera, PhD – University of Colorado Boulder

  Primary Investigator: Konstantinos Konstantopoulos, PhD – Johns Hopkins University