Cellular and Molecular Mechanobiology I: From Outside to Inside of the Cell

Track Chair(s)

• LT

  Luke (Lucas) Timmins, PhD

  Associate Professor
  Texas A&M University
  Houston, Texas, United States
• KM

  Kristen Mills

  Associate Professor
  Rensselaer Polytechnic Institute, United States

Session Chair(s)

• MR

  Megan Rexius
• 

  Matthew Bersi, PhD

  Assistant Professor, Mechanical Engineering & Materials Science
  Washington University in St. Louis
  St. Louis, Missouri, United States

Presentations:

• 8:30 AM - 8:45 AM PDT

  A Novel ECM Stiffness-driven FAK isoform Tunes Cell Mechanosensing in Breast Cancer
  

  Presenting Author: Martial Millet, MSc – Universite Laval

  Co-Author: Juliette Gouhier – Universite Laval

  Co-Author: William David Zakzuk Vivas – Universite Laval

  Co-Author: Olivier Chancy – Universite Laval

  Co-Author: Elise Tahon – Universite Laval

  Co-Author: Gabriel Khelifi – Universite Laval

  Co-Author: Samer Hussein – Universite Laval

  Last Author: Francois Bordeleau, PhD – Universite Laval

  Co-Author: Dwayne Stupack – UCSD

  Co-Author: Caree Carson – UCSD
• 8:45 AM - 9:00 AM PDT

  Mechanical-context-dependent Ezrin Force Regulation in Cancer Cells
  

  Presenting Author: Siyan He, ms – Duke University

  Primary Investigator: Brenton Hoffman, PhD – Duke University
• 9:00 AM - 9:15 AM PDT

  Validation of a Nanobody-Based Keratin Strain Sensor and It's Use in Keratinocyte Stretch
  

  Presenting Author: Sarah Seman, MS – The Ohio State University

  Primary Investigator: Daniel Conway – The Ohio State University
• 9:15 AM - 9:30 AM PDT

  Determining Force Thresholds in ssDNA-ssDNA Interactions for Mechanically Triggered Molecular Devices
  

  Presenting Author: Hasibul Hasan Hasib, MSc – Iowa State University

  Co-Author: Abigail Koep – Iowa State University

  Co-Author: Ian Schneider – Iowa State University

  Primary Investigator: Anwesha Sarkar – Iowa State University
• 9:30 AM - 9:45 AM PDT

  siRNA-mediated knockdown of ITGA11 offers a treatment for vocal fold scarring through reduced myofibroblast activation
  

  Presenting Author: Yashna Gupta – University of Pennsylvania

  Co-Author: Ryan M. Friedman – University of Pennsylvania

  Last Author: Riccardo L. Gottardi, PhD – University of Pennsylvania

  Primary Investigator: Riccardo L. Gottardi, PhD – University of Pennsylvania
• 9:45 AM - 10:00 AM PDT

  Biomechanical Profiling of Murine Fibroblasts in Triple-Negative Breast Cancer Microenvironments
  

  Presenting Author: Connor Nguyen – The University of Alabama at Birmingham

  Co-Author: Shalarria Cooper – The University of Alabama at Birmingham

  Primary Investigator: MK Sewell-Loftin – University of Alabama Birmingham

  Co-Author: Vaishali Bala, MEng – University of Alabama at Birmingham